Actor and comedian Gene Wilder died Monday of complications from Alzheimer’s, his family announced. He was 83. Wilder was best known for playing Willy Wonka in the 1971 film Willy Wonka & the Chocolate Factory, as well as his roles in the Mel Brooks comedies The Producers, Blazing Saddles, and Young Frankenstein. Brooks called Wilder one of the “truly great talents of our time,” and said he “blessed every film we did with his magic and he blessed me with his friendship.” In addition to starring in films, Wilder, a two-time Academy Award nominee, won an Emmy for his performance on several episodes of Will & Grace, and wrote a memoir and several fiction books. He is survived by his fourth wife, Karen, and his nephew, Jordan Walker-Pearlman. Wilder was preceded in death by his third wife, actress and comedian Gilda Radner, and his sister, Corinne, who died in January.